4. Entero-pancreatic Endocrine Function and Diabetes
نویسندگان
چکیده
منابع مشابه
Clinical utility of indigenously formulated single-vial lyophilized HYNIC-TOC kit in evaluating Gastro-entero Pancreatic neuro endocrine tumours
Objective(s): The objective of this study was to evaluate the performance and utility of 99mTc HYNIC-TOC planar scintigraphy and SPECT/CT in the diagnosis, staging and management of gastroenteropancreatic neuroendocrine tumors (GPNETs). Methods: 22 patients (median age, 46 years) with histologically proven gastroentero-pancreatic NETs underwent 99mTc HYNIC-TOC whole body scintigraphy and regi...
متن کاملExocrine and endocrine pancreatic function in diabetes mellitus and chronic pancreatitis.
EDITORIAL SYNOPSIS Endocrine and exocrine pancreatic function was studied in a small group of controlled patients and in patients with chronic pancreatitis and with mild diabetes mellitus. Patients with chronic pancreatitis showed impaired production of pancreatic enzyme and inadequate production of insulin but no close correlation between exocrine and endocrine function could be demonstrated. ...
متن کاملModeling Pancreatic Endocrine Cell Adaptation and Diabetes in the Zebrafish
Glucose homeostasis is an important element of energy balance and is conserved in organisms from fruit fly to mammals. Central to the control of circulating glucose levels in vertebrates are the endocrine cells of the pancreas, particularly the insulin-producing β-cells and the glucagon producing α-cells. A feature of α- and β-cells is their plasticity, an ability to adapt, in function and numb...
متن کاملPancreatic endocrine neoplasms: epidemiology and prognosis of pancreatic endocrine tumors.
Pancreatic endocrine tumors (PETs) are uncommon tumors with an annual incidence <1 per 100 000 person-years in the general population. The PETs that produce hormones resulting in symptoms are designated as functional. The majority of PETs are non-functional. Of the functional tumors, insulinomas are the most common, followed by gastrinomas. The clinical course of patients with PETs is variable ...
متن کاملChronic fractalkine administration improves glucose tolerance and pancreatic endocrine function.
We have previously reported that the fractalkine (FKN)/CX3CR1 system represents a novel regulatory mechanism for insulin secretion and β cell function. Here, we demonstrate that chronic administration of a long-acting form of FKN, FKN-Fc, can exert durable effects to improve glucose tolerance with increased glucose-stimulated insulin secretion and decreased β cell apoptosis in obese rodent mode...
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ژورنال
عنوان ژورنال: Nihon Naika Gakkai Zasshi
سال: 2019
ISSN: 0021-5384,1883-2083
DOI: 10.2169/naika.108.112a